A novel synthesis of xanthines: support for a new binding mode for xanthines with respect to adenosine at adenosine receptors

J Med Chem. 1990 Dec;33(12):3127-30. doi: 10.1021/jm00174a004.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Adenosine / metabolism*
  • Animals
  • Dogs
  • Humans
  • Molecular Conformation
  • Molecular Structure
  • Protein Binding
  • Rats
  • Receptors, Purinergic / metabolism*
  • Structure-Activity Relationship
  • Theophylline / chemistry
  • Theophylline / metabolism
  • Xanthines / chemical synthesis
  • Xanthines / chemistry
  • Xanthines / metabolism*

Substances

  • Receptors, Purinergic
  • Xanthines
  • Theophylline
  • Adenosine